HOW TO USE APRETUDE (CARBOTEGRAVIR)

 

APRETUDE: A Game-Changer in HIV Prevention

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APRETUDE is transforming HIV prevention with its extended protection and fewer doses, making it a stellar option. Say goodbye to daily pills, with improved adherence rates and increased user satisfaction thanks to APRETUDE.

 

Getting Started with APRETUDE

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Interested in APRETUDE? Begin by consulting your healthcare provider to check your eligibility. Your first visit will include a health assessment and the initial injection. Follow-up care ensures continuous protection and health monitoring.

 

Dosing Schedule

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Doctors might start treatment with daily 30mg cabotegravir tablets for a month before transitioning to the injectable form of APRETUDE to check tolerance. Alternatively, they may start directly with the APRETUDE injection, skipping the oral pills.

Initially, patients receive APRETUDE once a month for the first two months, then bi-monthly. Contact your physician to see if APRETUDE is right for you.

How to use Apretude 1			How to use Apretude 2
Month 1	1 inj starter dose 1		Month 1	Daily starter pills (30 days)
Month 2	1 inj starter dose 2		Month 2	1 inj (day 30 or within 3 days)
Month 3	-		Month 3	-
Month 4	1 inj		Month 4	1 inj
Month 5	-		Month 5	-
Month 6	1 inj		Month 6	1 inj
Month 7	-		Month 7	-
Month 8	1 inj		Month 8	1 inj
Month 9	-		Month 9	-
Month 10	1 inj		Month 10	1 inj
Month 11	-		Month 11	-
Month 12	1 inj		Month 12	1 inj

 

How to use Apretude when you party in Asia				How to use Apretude 2
JAN		1 inj starter dose 1		Month 1	Daily starter pills (30 days)
FEB		1 inj starter dose 2		Month 2	1 inj (day 30 or within 3 days)
MAR		-		Month 3	-
APR	Songkran gCircuit BKK	1 inj		Month 4	1 inj
MAY		-		Month 5	-
JUN	Pattaya Circuit	1 inj		Month 6	1 inj
JUL				Month 7	-
AUG	White Party Vietnam	1 inj		Month 8	1 inj
SEP		-		Month 9	-
OCT	Taipei Pride	1 inj		Month 10	1 inj
NOV		-		Month 11	-
DEC	Wonderfruit White Party BKK	1 inj		Month 12	1 inj

 

 

 

APRETUDE for Different Communities

Women APRETUDE caters to women’s unique health needs, providing a reliable, hassle-free HIV prevention option.

Men For men, APRETUDE eliminates the daily pill burden, offering consistent protection without daily reminders.

Gay Men APRETUDE benefits gay men by improving adherence and offering a discreet prevention method.

Transgender Individuals Transgender individuals face unique healthcare challenges. APRETUDE supports transgender health by offering an effective, convenient HIV prevention option.

 

Efficacy of Apretude for all populations

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Based on the research study

	Injectable PrEP Apretude Efficacy in Different Populations
Route or Sex	Straight Men	Straight Women	Gay and Bisexuals	TransWomem	TransMen
Oral Sex	more than 99%	more than 99%	more than 99%	more than 99%	more than 99%
Anal Sex	more than 99%	more than 99%	more than 99%	more than 99%	more than 99%
Vaginal Sex	more than 99%	more than 99%	more than 99%	more than 99%	more than 99%

SUPERIOR HIV PROTECTION VS TRUVADA

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STUDY IN CISGENDER MEN AND TRANSGENDER WOMEN

Significantly more people stayed HIV-negative on APRETUDE vs TRUVADA during the study.

69% reduction in the risk of acquiring HIV-1 with APRETUDE (0.37/100 person-years) vs TRUVADA (1.22/100 person-years)

 

 

 

 

STUDY IN CISGENDER WOMEN

 

 

 

Cost of APRETUDE

In Thailand, VIIV Healthcare has priced APRETUDE, the new injectable PrEP, at 19,500 THB per dose every two months.

 

Efficacy of Apretude for all populations

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Based on the research study

	Injectable PrEP Apretude Efficacy in Different Populations
Route or Sex	Straight Men	Straight Women	Gay and Bisexuals	TransWomem	TransMen
Oral Sex	more than 99%	more than 99%	more than 99%	more than 99%	more than 99%
Anal Sex	more than 99%	more than 99%	more than 99%	more than 99%	more than 99%
Vaginal Sex	more than 99%	more than 99%	more than 99%	more than 99%	more than 99%

 

Benefits of Injectable PrEP

APRETUDE (cabotegravir) offers numerous benefits as a long-acting HIV pre-exposure prophylaxis (PrEP) option:

• High Efficacy: Clinical trials show APRETUDE significantly reduces the risk of HIV-1 acquisition compared to daily oral PrEP, with over 99% effectiveness in real-world studies.
• Convenience: Administered as an injection every two months, APRETUDE removes the need for daily adherence.
• Improved Adherence: The long-acting nature of APRETUDE helps improve adherence to HIV prevention by removing the burden of daily pills.
• Reduction in Stigma and Anxiety: Real-world studies indicate APRETUDE reduces stigma and anxiety associated with daily oral PrEP, contributing to better mental health and quality of life.
• Diverse Population: Clinical trials involved a diverse range of participants, showing APRETUDE's broad applicability.
• Long-Lasting Protection: Each injection provides two months of continuous protection, offering reliable and sustained

 

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